Variety is reporting that Horta died of a self-inflicted gunshot wound.
Ugly Betty, starring America Ferrera, ran for four seasons on ABC from 2006 to 2010. It was adapted from the hit Colombian telenovela Yo soy Betty, la fea. Horta served as showrunner and head writer on the comedy-drama.
Horta, who was born in Miami to Cuban parents and majored in film at NYU.
His big break came in 1998 when he wrote the screenplay for horror-thriller Urban Legend. The script was turned into a successful feature starring Jared Leto and Alicia Witt.
Horta’s most recent credit was for writing the 2015 TV movie The Curse of the Fuentes Women.
Silvio Horta was 45.
(Photo, Avalon; via Variety)